Page 35 - brain-eBook

Team Project Name Yang Ming Chiao Tung University, Department of

Decoding pain sensitivity in migraine with Neurology at Taipei Veterans General Hospital,
multimodal brainstem-based neurosignature deep phenotyping, QST, gene, biochemical
signatures, brainstem EEG, functional connectivity,
Research Project central sensitization, integrated image analysis,

This comprehensive project aims to decipher the deep learning accelerated MRI pre-processing,
key mechanisms underlying the highly dynamic medical-grade wearable BCI system, AI medical
and dysregulated pain processing in migraine, cloud platform, animal model, cortical spreading
particularly within the brainstem and other deep depression, nitroglycerin, raphe nucleus, nucleus
brain regions, utilizing a multi-modal approach. tractus solitarius, parabrachial nucleus, amygdala,
We aim to combine deep phenotyping analysis, hippocampus, brainstem
deep brain region exploration, and deep learning Global Cooperation
modeling within a multi-modal research framework.
This approach, complemented by fundamental The technologies and research areas encompassed
experiments, is designed to decode the roles within this project, including magnetic resonance
played by the brainstem and other deep brain imaging (MRI) and functional MRI techniques,
regions in the pathophysiology of migraine. Based brainstem electroencephalography, quantitative
on the research outcomes, we aim to develop sensory testing, wearable brain-machine interface
innovative technologies and products, ultimately development, migraine animal models, and
realizing the goal of applying neurotechnology fundamental research, all hold potential for
products or techniques in clinical settings. international collaboration.

By optimizing diagnostic and treatment strategies, Our team is proactively exploring avenues
we expect to significantly enhance patients' quality for international cooperation to foster the
of life and alleviate the substantial socioeconomic establishment of substantial research partnerships
burden imposed by migraine. with international collaborators.
Key Words Project Web Page

Brain Research Center at National Yang Ming
Chiao Tung University, College of Medicine at
National Yang Ming Chiao Tung University, Institute
of Electrical and Control Engineering at National

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