Page 33 - brain-eBook

Team Project Name basis and clinical impacts of " ೭೨ " It will also

Neurobiological basis of sngception and its establish new concepts in pain medicine, allowing
therapeutic potential for neurological disorders (II) the sensation of " ೭ " to be recognized, diagnosed,
Research Project and treated appropriately for patients.

In Chinese society, the term " ೭೨ " (sng-pain) Key Words
is commonly used to describe pain, with "sng" ASIC3, sng, pain, fibromyalgia, linguistics,
representing the sensation of soreness. However, machine learning, Academia Sinica, National Taipei
chronic sng, a prevalent complaint in many chronic University of Science and Technology, Kaohsiung
pain conditions, significantly impacts patients' Medical University Hospital, National Taiwan
quality of life. Unfortunately, modern medicine University, National Taiwan University Hospital,
tends to overlook the severity of this impact, Taipei Medical University Hospital
often treating sng as a mild symptom of pain. Global Cooperation
Our research confirms that " ೭ " and " ೨ " are
distinct somatosensory nerve functions, presenting Establishing a world-class "Sngception Research
as different symptoms in various neurological Center" in Taiwan, we aim to conduct educational
conditions. outreach and initiate cross-cultural research on
"sng" and "pain" among diverse linguistic and
cultural communities. This endeavor includes
Our central hypothesis suggests that proprioceptive
neurons, potentially a subset of sng-sensitive developing clinical diagnostic tools and an artificial
neurons, may involve the third type of acid- intelligence-based facial and behavioral recognition
sensing ion channel (ASIC3) as one of the system. The system will interpret the sensation of "
receptor molecules transmitting the sensation ೭ " across different ethnic groups and animals.
of sng. To address the lack of methodology and
theory in investigating sng, we will explore the The objective is to create a globally renowned
differences between " ೭ " and " ೨ "and identify research center focusing on proprioceptive
the neural pathways responsible for proprioceptive sensation, fostering education and collaboration
sensations related to " ೭ " in the brain. We aim to across various language and cultural backgrounds.
Additionally, the development of advanced
understand how these sensations are transmitted, diagnostic tools and AI-based recognition systems
processed, decoded, and linguistically expressed. will enhance our understanding of "sng" in diverse
In clinical practice, we will delve into conditions populations and species.
such as spinal degeneration, fibromyalgia, restless
legs syndrome, and myofascial pain syndrome, Project Web Page
conducting in-depth investigations into the
prevalence of sng, its pathophysiology, and the role
of acid-sensitive ion channels.

The research outcomes will contribute to a
redefined understanding of the neuroscientific

32 33