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Team Project Name                                  classifying blood oxygen activity features in brain

            Digital Therapeutic Approaches to Brain            tissues.
            Neuromodulation for Anxiety Disorders              Key Words
            Research Project                                   Digital Therapeutic, Transcranial Stimulation,
                                                               Functional Near-Infrared Spectroscopy, Neural
            The team developed a near-infrared                 Feedback, Anxiety
            spectroscopy(fNIRS) instrument for real-time
            monitoring of anxiety-related brain activity,      Global Cooperation
            exploring the application of AI biomarkers in the
            diagnosis and assessment of the progression of     The team is developing a near-infrared
            anxiety disorders. They integrated a high-definition   spectroscopy instrument for real-time monitoring
            transcranial electrical stimulation(HD-tES)        of brain activity in anxiety disorders. We are
            treatment system, along with a digital cognitive   exploring the application of AI-based biomarkers
            therapy system using fNIRS as neural feedback,     in the diagnosis and assessment of the course of
            to meet the unmet needs in clinical cognitive and   the disease. The team is also integrating a high-
            motor rehabilitation training.                     precision focal transcranial electrical stimulation
                                                               therapy system, as well as a digital behavioral
            In previous studies with healthy subjects, the team   cognitive therapy system using fNIRS as
            found that simultaneous neural stimulation of both   neurofeedback, to meet the unmet needs in clinical
            hemispheres significantly enhanced oxygenation     cognitive and motor rehabilitation training.
            capacity during exercise training. The effects not
            only showed a significant improvement during the   We  are looking forward to international
            intervention but also persisted for some time after   collaboration in executing clinical research projects
            completion. In stroke patients undergoing upper    to expand digital medical methods in the fields of
            limb rehabilitation training intervention, the results   neural regulation and neurofeedback.
            indicated significant improvements in various      Project Web Page
            functional indicators compared to the control group.
            Furthermore, the team discovered that subjects,
            when  exposed to  different emotional  stimuli,
            achieved an overall classification accuracy of
            95.7%  through  machine  learning  algorithms


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