Page 15 - brain-eBook

Team Project Name (3) Clinical Trials: Multiple first-in-man clinical

Focused ultrasound as a new tool to explore CNS trials of focused ultrasound neural modulation are
underway domestically.
neural functions
Research Project Key Words

This project aims to establish an innovative Focused ultrasound, neuromodulation, brain
ultrasound neural modulation platform. During functional connectivity, fMRI, PET, epilepsy
the project's execution, apart from successfully Global Cooperation
developing ultrasound neural modulation tools and Our team can provide expertise in establishing
applying them as a source of neural stimulation for focused ultrasound systems for applications
exploring functional brain connectivity, the project ranging from cellular studies, pre-clinical small
has also successfully integrated the ultrasound animal research, pre-clinical large animal studies,
system with various analytical platforms, including to advancing technologies for clinical trials.
fMRI, PET, EEG, MEP, and optical platforms, for
brain functional connectivity analysis.
Our team's capabilities also encompass techniques
such as MEP neural assessment, EEG neural
Highlights during the project execution include: assessment, GCaMP ion channel assessment,
(1)In-House Instrumentation: A significant fMRI connectivity evaluation, PET neural imaging
achievement of the project to date is the initial assessment, and other methods that can be
completion of a self-made small animal neural applied in pre-clinical animal experiment analysis.
modulation-focused ultrasound device entirely Project Web Page
developed within the laboratory, with a pending
patent application.
(2) International Collaboration: Collaborative
efforts with Stanford University in the field of
ultrasound neural modulation have resulted in joint
publications in top-tier journals with high impact
factors.

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